Antipsychotic-induced vacuous chewing movements and extrapyramidal side effects are highly heritable in mice
نویسندگان
چکیده
منابع مشابه
Extrapyramidal side-effects and antipsychotics: are second-generation agents
Peluso et al report on the differential effect of first-generation antipsychotics (FGAs) v. second-generation antipsychotics (SGAs) in ameliorating or exacerbating extrapyramidal side-effects (EPS) in a secondary analysis of the CUtLASS-1 trial data. They report their findings as ‘essentially null’ and mention that there is weak evidence for clinically significant differences in emergent or rel...
متن کاملExtrapyramidal side-effects and antipsychotics: are second-generation agents
Peluso et al report on the differential effect of first-generation antipsychotics (FGAs) v. second-generation antipsychotics (SGAs) in ameliorating or exacerbating extrapyramidal side-effects (EPS) in a secondary analysis of the CUtLASS-1 trial data. They report their findings as ‘essentially null’ and mention that there is weak evidence for clinically significant differences in emergent or rel...
متن کاملExtrapyramidal side-effects and antipsychotics: are second-generation agents
Peluso et al report on the differential effect of first-generation antipsychotics (FGAs) v. second-generation antipsychotics (SGAs) in ameliorating or exacerbating extrapyramidal side-effects (EPS) in a secondary analysis of the CUtLASS-1 trial data. They report their findings as ‘essentially null’ and mention that there is weak evidence for clinically significant differences in emergent or rel...
متن کاملTreatment recommendations for extrapyramidal side effects associated with second-generation antipsychotic use in children and youth.
BACKGROUND/OBJECTIVE Antipsychotic use in children is increasing. The purpose of the present article was to provide guidance to clinicians on the clinical management of extrapyramidal side effects of second-generation antipsychotics. METHODS Published literature, key informant interviews, and discussions with panel members and stakeholder partners were used to identify key clinical areas of g...
متن کاملPharmacogenetics of antipsychotic-induced side effects
Currently available antipsychotic drugs (APDs) carry significant though highly variable, liability to neurologic and metabolic side effects. Pharmacogenetics approaches offer the possibility of identifying patient-specific biomarkers for predicting risk of these side effects. To date, a few single nucleotide polymorphisms (SNPs) in a handful of genes have received convergent support across mult...
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ژورنال
عنوان ژورنال: The Pharmacogenomics Journal
سال: 2010
ISSN: 1470-269X,1473-1150
DOI: 10.1038/tpj.2010.82